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JE

Tick-borne encephalitis (TBE) is a viral infectious disease from tick bites, involving the central nervous system. The disease most often manifests as meningitis, encephalitis, or meningoencephalitis.

The TBE virus is found naturally in small animals such as mice and voles and in domestic animals such as sheep, goats and cattle. Ticks are the main carriers of the virus, picking up the virus when they feed on the blood of an infected animal. Once the tick is infected with the virus, it carries this for life. Humans become infected with TBE when they are bitten by an infected tick.

The virus is present in the tick’s saliva, which contains a natural anaesthetic, so you may not notice you have been bitten. It is important to check your body regularly for ticks when in risk areas.

Ticks live in forests, woods, grasslands, riverside meadows, marshes, brushwood and shrublands. They usually live in the undergrowth, where they can easily get onto the clothes or skin of passers-by.

Very rarely, drinking unpasteurised milk from infected animals, especially goats, can expose you to the TBE virus.

The initial symptoms of TBE usually occur 7–14 days after a tick bite. Two-thirds of people infected with TBE get these symptoms, while the other third will have no symptoms. Symptoms include:

- Fever (temperature of 38C (100.4F) or above)

- Headache and tiredness

- Muscle pain

- Feeling sick

These first-stage symptoms usually last between one and eight days. After this, there are no symptoms for the following 1–20 days. Around one-third of those who experience first-stage symptoms go on to develop the second phase of the disease.

The second phase of the disease starts with a sudden rise in temperature. The virus starts to affect your central nervous system (brain and spinal cord), which can result in:

- meningitis - inflammation of the membranes surrounding the brain and spinal cord, and /or

- encephalitis - inflammation of the brain

These conditions can sometimes cause paralysis (inability to move certain body parts). (People can sometimes progress to second stage symptoms without having any first stage symptoms)

In the second stage of illness, children usually develop meningitis. Around one-third of people who experience second-stage symptoms will develop encephalitis. Adults over the age of 40 are particularly vulnerable to encephalitis. There is a higher risk of death in people over the age of 60.

Viral meningitis is not as serious as bacterial meningitis, which is life-threatening. But the viral form of the condition can still cause a range of unpleasant symptoms, including:

- headaches

- fever (temperature of 38C (100.4F) or above)

- chills

- muscle or joint pain

In severe cases of viral meningitis, symptoms can also include: feeling sick being sick aversion to bright light (photophobia)

Symptoms of encephalitis Encephalitis also usually begins with flu-like symptoms, such as a headache and generally feeling unwell. More serious symptoms follow over the space of a few hours or days. These include:

- a high temperature (38C (100.4F) or above)

- feeling sick being sick

- changes in mental state, such as confusion drowsiness or disorientation

- seizures (fits)

- photophobia

- inability to speak

- paralysis and/or stiff neck

- uncharacteristic behaviour, such as being unusually aggressive 

If a doctor thinks you may have tick-borne encephalitis (TBE), they will ask about your symptoms, medical history, where you have been travelling and if you think you may have been bitten by a tick.

They will then test your blood for antibodies to the virus. Antibodies are proteins produced by your immune system to fight infection. If antibodies are found, you may need further tests to confirm the results.

Further tests may include: an MRI scan (brain scan to check for signs of inflammation indicating encephalitis) a lumbar puncture, where a sample of your spinal fluid is checked for the TBE virus and signs of inflammation of the membranes covering the brain and spinal cord

If you are infected with tick-borne encephalitis (TBE) and do not experience any symptoms, or only mild first-stage symptoms, you will usually get better without treatment. Iburofen or paracetamol can be taken to relieve any flu-like symptoms.

In cases of stage-two TBE, there is no specific medication used to treat the infection. If you develop a severe form of viral meningitis and /or encephalitis, you need to go to hospital where you will be given supportive treatments such as intravenous fluids, help with breathing and nursing care to support your body while you recover.

Around 1 in 8 people with a second-stage infection need to be admitted to an intensive care unit (ICU), where doctors will aim to: control any complications, such as seizures or dehydration prevent long-term complications such as memory loss or epilepsy

Malaria

They are mainly found in forested areas of central, eastern and northern Europe, including Austria, Bosnia-Herzegovina, Croatia, Estonia, Latvia, Czech Republic, Slovakia, Germany, Hungary, Macedonia, Montenegro, Poland, Serbia, Slovenia, Switzerland, Russia and Ukraine.

There are also two sub-types of TBE known as: Far Eastern – found in eastern Russia during spring and summer and in some countries in East Asia, particularly forested regions of China and Japan Siberian – found in Siberia.

Tick-borne encephalitis (TBE) can be prevented by avoiding tick bites when in risk areas. The best way to lower your risk of TBE is to avoid tick bites as much as possible when in risk areas:

Insect repellent clothing and accessories provide protection from unwanted bites.

You can also treat your clothes with insecticides such as permethrin.

Using insect repellent containing DEET may also help prevent getting bitten.

Check your body for ticks regularly. Common places to find them are the hair line, behind the ears, elbows, backs of knees, the groin and armpits.

Avoid eating and drinking milk and unpasteurised dairy products in countries where there is a high risk of TBE.

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